Cancer BiologybioRxiv
SHARPIN enhances ferroptosis in synovial sarcoma cells via NF-κB- and PRMT5-mediated PGC1α reduction
H. Tamiya, N. Urushihara, K. Shizuma…·S. Kakunaga
This study shows SHARPIN promotes ferroptosis in synovial sarcoma cells by reducing PGC1α via NF-κB and PRMT5 pathways, enhancing sensitivity to ferroptosis inducers.
DOI 10.3390/cancers15133484