Author

S. Kaonis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3 Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:ChIP-seq· 3 Research Focus:chromatin & epigenetic regulation· 3 Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Assay:imaging· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

S. Ghosh· 4 shared A. K. Scott· 1 shared B. Hine· 1 shared B. K. Hadland· 1 shared B. M. S. Martin· 1 shared B. Seelbinder· 1 shared C. P. Neu· 1 shared E. Babaeva· 1 shared

Activity by Year

2021-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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4 shared papersBiophysics

S. Ghosh

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Hyperoxia Induced Alteration of Chromatin Structure in Bone Marrow Derived Primary Mesenchymal Stromal Cells

L. Monroe, S. Kaonis, N. Calahan, N. Kabi, S. Ghosh

This study investigates how hyperoxia alters chromatin structure in mesenchymal stromal cells using imaging techniques and finds spatiotemporal variability in chromatin remodeling and its inhibition by GSK126.

bioRxiv · Dec 29, 2023 · PreprintBiophysics

Chromatin Remodeling and Epigenetic Modifications in Planar Cell Migration

J. Forman, B. Hine, S. Kaonis, S. Ghosh

This study shows that chromatin remodeling and epigenetic modifications influence cell migration speed and wound closure efficiency on planar substrates.

bioRxiv · Dec 21, 2023 · PreprintBiophysics

Chromatin Profiling of CBFA2T3-GLIS2 AMLs Identifies Key Transcription Factor Dependencies and BRG1 Inhibition as a Novel Therapeutic Strategy

S. Kaonis, J. L. Smith, N. Katiyar, M. Merrill, T. Hylkema, S. Namciu, Q. Le, E. Babaeva, T. Ikeda, S. M. Morris, E. Girard, S. Furuyama, R. Ries, I. Bernstein, S. Meshinchi, , J. F. Sarthy

This study identifies BRG1 inhibition as a therapeutic strategy for CBFA2T3-GLIS2 AML by analyzing chromatin profiles and CRISPR dependencies.

bioRxiv · Aug 30, 2023 · PreprintCancer Biology

Characterization of Mechanics Driven Heterogeneity in Mesenchymal Stromal Cells

S. Kaonis, Z. Aboellail, S. Ghosh

This study shows that abnormal mechanical environments cause phenotypic heterogeneity in human bone marrow-derived mesenchymal stromal cells, identified through high-resolution imaging and image analysis.

bioRxiv · Jul 25, 2022 · PreprintBioengineering

Dedifferentiation alters chondrocyte nuclear mechanics during in vitro culture and expansion

S. Ghosh, A. K. Scott, B. Seelbinder, J. E. Barthold, B. M. S. Martin, S. Kaonis, S. E. Schneider, J. T. Henderson, C. P. Neu

This study shows that dedifferentiated chondrocytes exhibit altered nuclear mechanics and gene expression of nuclear envelope proteins, which may contribute to further dedifferentiation.

bioRxiv · Apr 26, 2021Biophysics