Author

S. Kengen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:CRISPR screen· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

A. Arifah· 1 shared A. J. R. Heck· 1 shared A. Konijnenberg· 1 shared A. M. J. J. Bonvin· 1 shared B. Perez· 1 shared B. Steigenberger· 1 shared C. Ingham· 1 shared C. Patinios· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBioengineering

A. Arifah

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Author profile →

2 papers

Recent·Most cited

Thriving in the heat - Lysine acetylation stabilizes the quaternary structure of a Mega-Dalton hyperthermoactive PEP-synthase

P. Albanese, W. Song, S. v. Keulen, J. Koendjbiharie, F. Koh, B. Steigenberger, T. Vincent, A. Konijnenberg, A. J. R. Heck, S. Kengen, A. M. J. J. Bonvin, F. Förster, R. A. Scheltema

The paper investigates how lysine acetylation stabilizes the structure of a hyperthermoactive PEP-synthase from Pyrococcus furious, revealing its role in maintaining function under extreme temperatures.

bioRxiv · Aug 11, 2022 · PreprintBiochemistry

SIBR-Cas enables host-independent and universal CRISPR genome engineering in bacteria

C. Patinios, S. Creutzburg, A. Arifah, B. Perez, C. Ingham, S. Kengen, J. van der Oost, R. Staals

This paper introduces SIBR-Cas, a CRISPR-based genome engineering tool that works universally in bacteria without host factors or exogenous recombinases, enabling gene knockouts in species with poor homologous recombination.

bioRxiv · Apr 26, 2021Bioengineering