Author

A. Konijnenberg

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Biophysics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:bacteria (other)· 2 Research Focus:chromatin & epigenetic regulation· 2 Assay:cryo-EM· 1 Research Focus:host-pathogen & immune response· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

F. Sobott· 2 shared A. A. Makarov· 1 shared A. Botman· 1 shared A. J. R. Heck· 1 shared A. M. J. J. Bonvin· 1 shared A. M. Lau· 1 shared A. N. Volkov· 1 shared A. Onur· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 8 mutual co-author links

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2 shared papersBiophysics

F. Sobott

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Cryo-EM of soft-landed β-galactosidase: Gas-phase and native structures are remarkably similar

T. K. Esser, J. Boehning, A. Onur, D. K. Chinthapalli, L. Eriksson, M. Grabarics, P. Fremdling, A. Konijnenberg, A. A. Makarov, A. Botman, C. Peter, J. L. P. Benesch, C. V. Robinson, J. Gault, L. Baker, , S. Rauschenbach

The paper uses cryo-EM to determine the gas-phase structure of β-galactosidase at 2.6 Å resolution, showing structural similarity to its native state.

bioRxiv · Aug 17, 2023 · PreprintBiochemistry

Thriving in the heat - Lysine acetylation stabilizes the quaternary structure of a Mega-Dalton hyperthermoactive PEP-synthase

P. Albanese, W. Song, S. v. Keulen, J. Koendjbiharie, F. Koh, B. Steigenberger, T. Vincent, A. Konijnenberg, A. J. R. Heck, S. Kengen, A. M. J. J. Bonvin, F. Förster, R. A. Scheltema

The paper investigates how lysine acetylation stabilizes the structure of a hyperthermoactive PEP-synthase from Pyrococcus furious, revealing its role in maintaining function under extreme temperatures.

bioRxiv · Aug 11, 2022 · PreprintBiochemistry

Large-scale conformational changes of FhaC provide insights into the two-partner secretion mechanism

G. Sicoli, A. Konijnenberg, J. Guerin, S. Hessmann, E. Del Nero, O. Hernandez-Alba, S. Lecher, G. Rouaut, L. Mueggenburg, H. Vezin, S. CIANFERANI, F. Sobott, R. Schneider, F. Jacob-Dubuisson

The paper investigates conformational changes in FhaC, a TpsB transporter, revealing how it facilitates protein secretion without external energy sources through intrinsic dynamics.

bioRxiv · Nov 9, 2021Biophysics

Vibrio cholerae ParE2 toxin modulates its operon transcription by stabilization of an antitoxin DNA ruler

G. Garcia-Rodriguez, Y. A. Girardin, R. K. Singh, A. N. Volkov, A. Konijnenberg, F. Sobott, D. Charlier, R. Loris

This study investigates how ParE2 toxin modulates its operon transcription by stabilizing the antitoxin DNA ruler through protein-DNA interactions and structural analysis.

bioRxiv · Mar 22, 2021Microbiology

Perturbed structural dynamics underlie inhibition and altered specificity of the multidrug efflux pump AcrB

E. Reading, Z. Ahdash, C. Fais, V. Ricci, X. Wang-Kan, E. Grimsey, J. W. Stone, G. Malloci, A. M. Lau, H. Findlay, A. Konijnenberg, P. J. Booth, P. Ruggerone, A. V. Vargiu, L. J. V. Piddock, A. Politis

The paper investigates the structural dynamics of the AcrB efflux pump, showing how inhibitors and mutations affect its function and substrate specificity.

bioRxiv · Apr 27, 2020Biochemistry