IGF2BP2 is Induced by Stress in the Heart and Mediates Dilated Cardiomyopathy
M. Krumbein, F. Oberman, Y. Cinnamon, M. Golomb, D. May, G. Vainer, V. Belzer, K. Meir, I. Fridman, J. Haybaeck, G. Poelzl, I. Kehat, R. Beeri, S. Kessler, J. K. Yisraeli
This study shows that IGF2BP2, induced by stress in the heart, causes dilated cardiomyopathy when overexpressed and can be reversed by its downregulation.
bioRxiv · Nov 3, 2022Cell Biology