Cancer BiologybioRxiv
TET2 binding to enhancers facilitates transcription factor recruitment in hematopoietic cells
K. Rasmussen, I. Berest, S. Kessler…·K. Helin
This study shows TET2 binding to enhancers in hematopoietic cells supports transcription factor recruitment, and its loss disrupts chromatin binding of CDX4, linking epigenetic regulation to disease.