Author

K. Helin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

D. Shlyueva· 1 shared E. Karjalainen· 1 shared F. Ambri· 1 shared G. S. Vassilou· 1 shared I. Berest· 1 shared J. Christensen· 1 shared J. Zaugg· 1 shared K. D. Rasmussen· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperCell Biology

D. Shlyueva

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3 papers

Recent·Most cited

An integrated approach to study chromatin and transcriptional dynamics throughout the cell cycle without pharmacological inhibition

D. Shlyueva, S. Teed-Singer, Y. Zhan, R. Koche, K. Helin

The paper compares chromatin and transcriptional dynamics across cell cycle phases in mESCs using different synchronization methods, finding that CDK1 inhibitor synchronization best mimics G2/M phase.

bioRxiv · Jun 18, 2022 · PreprintCell Biology

COMPARE, an ultra-fast and robust suite for multiparametric screening, identifies phenotypic drug responses in acute myeloid leukemia

M. Chalabi Hajkarim, E. Karjalainen, M. Osipovitch, K. Dimopoulos, S. L. Gordon, F. Ambri, K. D. Rasmussen, K. Gronbaek, K. Helin, K. Wennerberg, K. J. Won

bioRxiv · Jan 8, 2021Cancer Biology

TET2 binding to enhancers facilitates transcription factor recruitment in hematopoietic cells

K. Rasmussen, I. Berest, S. Kessler, K. Nishimura, L. Simon-Carrasco, G. S. Vassilou, M. T. Pedersen, J. Christensen, J. Zaugg, K. Helin

This study shows TET2 binding to enhancers in hematopoietic cells supports transcription factor recruitment, and its loss disrupts chromatin binding of CDX4, linking epigenetic regulation to disease.

bioRxiv · May 31, 2018Cancer Biology