Common allotypes of ER aminopeptidase 1 have substrate-dependent and highly variable enzymatic properties
H. P. Jonathan, I. Temponeras, J. Kuiper, A. Cortes, J. Korczynska, S. Kitchen, E. Stratikos
The paper characterizes the enzymatic properties of common ERAP1 allotypes and finds they show substrate-dependent activity variation, with one allotype consistently low in activity.
bioRxiv · Nov 19, 2020Biochemistry