Structural and Biological Evaluations of a Non-Nucleoside STING Agonist Specific for Human STINGA230 Variants
Z. Tang, J. Zhao, Y. Li, S. Tomer, M. Selvaraju, N. Tien, D. Sun, D. K. Johnson, A. Zhen, P. Li, J. Wang
The paper characterizes BDW568, a non-nucleoside STING agonist, showing it activates STINGA230 variants in human cells and mimics endogenous ligands.
bioRxiv · Jul 2, 2023 · PreprintPharmacology & Toxicology