Author

S. L. Sarkar

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Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:structural biology· 1

Frequent Co-Authors

A. Singharoy· 1 shared D. Tan· 1 shared E. Nudler· 1 shared G. L. Lee· 1 shared J. Miratsky· 1 shared J. Vant· 1 shared K. Dryden· 1 shared M. Brenowitz· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

A. Singharoy

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1 paper

Recent·Most cited

Structural mechanism of HP1-dependent transcriptional repression and chromatin compaction

V. Sokolova, J. Miratsky, V. Svetlov, M. Brenowitz, J. Vant, T. S. Lewis, K. Dryden, G. L. Lee, S. L. Sarkar, E. Nudler, A. Singharoy, D. Tan

This study determines the cryo-EM structure of HP1 bound to an H2A.Z nucleosome, revealing two binding sites and their roles in transcriptional repression and chromatin compaction.

bioRxiv · Nov 30, 2023Biochemistry