BiochemistrybioRxiv
Structural mechanism of HP1-dependent transcriptional repression and chromatin compaction
V. Sokolova, J. Miratsky, V. Svetlov…·D. Tan
This study determines the cryo-EM structure of HP1 bound to an H2A.Z nucleosome, revealing two binding sites and their roles in transcriptional repression and chromatin compaction.
DOI 10.1016/j.str.2024.09.013