BiochemistrybioRxiv
Avidity observed between a bivalent inhibitor and an enzyme monomer with a single active site
S. Lacham-Hartman, Y. Shmidov, E. Radisky…·N. Papo
The paper demonstrates avidity in a bivalent inhibitor interacting with a monomeric enzyme, showing enhanced binding affinity through cooperative binding despite the absence of receptor clustering.
DOI 10.1371/journal.pone.0249616