Applications of genetic-epigenetic tissue mapping for plasma DNA in prenatal testing, transplantation and oncology
W. Gai, Z. Zhou, S. Agbor-Enoh, X. Fan, S. Lian, P. Jiang, S. H. Cheng, J. Wong, S. L. Chan, M. K. Jang, Y. Yang, R. H. S. Liang, W. K. Chan, E. S. K. Ma, T. Y. Leung, , Y. M. D. Lo
This paper introduces GETMap, a method to determine tissue origin of plasma DNA carrying genetic variants, validated across prenatal testing, transplantation, and oncology scenarios.
bioRxiv · Nov 13, 2020Physiology