TriPer, an optical probe tuned to the endoplasmic reticulum, tracks H2O2 consumption by glutathione
E. P. Melo, C. Lopes, P. Gollwitzer, S. Lortz, S. Lenzen, I. Mehmeti, C. F. Kaminski, D. Ron, E. Avezov
The paper develops TriPer, an optical probe that detects H2O2 in the ER, revealing glutathione's role in H2O2 turnover during protein folding.
bioRxiv · Feb 3, 2017Cell Biology