S. Marcotti

Derivation and simulation of a computational model of active cell populations: How overlap avoidance, deformability, cell-cell junctions and cytoskeletal forces affect alignment

This study develops and simulates a computational model to understand how cell properties affect collective alignment, finding optimal self-propulsion and overlap avoidance ratios, and the role of deformability and junctions.

Characterisation and correction of polarisation effects in fluorescently labelled fibres

The paper identifies polarisation effects in fluorescently labelled fibres and introduces a correction method to improve fibre alignment analysis.

Bridging Imaging Users to Imaging Analysis - A community survey

The paper surveys imaging users and developers to identify needs and gaps in image analysis tools and education, highlighting demands for documentation, tutorials, and user-friendly software.

A Workflow for Rapid Unbiased Quantification of Fibrillar Feature Alignment in Biological Images

This paper introduces AFT, a workflow using 2D FFT to quantify fibrillar feature alignment in microscopy images, showing advantages in flexibility, parameter efficiency, and computational speed.

The glycocalyx affects the mechanotransductive perception of the topographical microenvironment

This study shows that glycocalyx configuration influences mechanotransductive responses of PC12 cells to nanotopographical cues through changes in actin dynamics and force loading.

Nance-Horan Syndrome-like 1 protein negatively regulates Scar/WAVE-Arp2/3 activity and inhibits lamellipodia stability and cell migration.

This study identifies NHSL1 as a negative regulator of Scar/WAVE-Arp2/3 activity, inhibiting lamellipodia stability and cell migration.

Comparative study of contact repulsion in control and mutant macrophages using a novel interaction detection

This paper compares contact-repulsion behavior in control and Shot3 mutant macrophages using a novel interaction detection framework called macrosight.

A multi-structural finite element model to simulate atomic force microscopy nanoindentation of single cells

The paper develops a multi-structural finite element model to simulate AFM nanoindentation of single cells and compares its results with experimental stiffness measurements.