Derivation and simulation of a computational model of active cell populations: How overlap avoidance, deformability, cell-cell junctions and cytoskeletal forces affect alignment
V. Leech, F. Kenny, S. Marcotti, T. Shaw, B. Stramer, A. Manhart
This study develops and simulates a computational model to understand how cell properties affect collective alignment, finding optimal self-propulsion and overlap avoidance ratios, and the role of deformability and junctions.
bioRxiv · Feb 2, 2024Cell Biology