Molecular Basis of Host-Adaptation Interactions between Influenza Virus Polymerase PB2 Subunit and ANP32A
A. C. Zarco, S. Kalayil, D. Maurin, N. Salvi, E. Delaforge, S. Milles, M. R. Jensen, D. J. Hart, S. Cusack, M. Blackledge
This study identifies molecular interactions between influenza PB2 subunit variants and ANP32A that explain host adaptation and species-specific restriction of viral replication.
bioRxiv · Mar 18, 2020Biophysics