BiophysicsbioRxiv
Modulating long-range energetics via helix stabilization: a case study using T4 lysozyme
S. N. Rosemond, K. M. Hamadani, J. H. D. Cate, S. Marqusee
This study investigates long-range energetic coupling in T4 lysozyme by analyzing a circularly permuted variant, showing that helix stabilization enhances subdomain stability through salt bridge interactions.
DOI 10.1002/pro.3521