Author

S. Noell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 3 Organism:virus· 2 Assay:metabolomics· 1 Research Focus:phylogenetics / evolution· 1 Assay:proteomics· 1

Frequent Co-Authors

C. M. Steppan· 2 shared L. Aschenbrenner· 2 shared Y. Zhu· 2 shared A. D. Mesecar· 1 shared A. E. Stewart· 1 shared A. K. Chatterjee· 1 shared A. S. Anderson· 1 shared B. Bolanos· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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2 shared papersBiochemistry

C. M. Steppan

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Structural basis for Nirmatrelvir in vitro efficacy against SARS-CoV-2 variants

S. E. Greasley, S. Noell, O. Plotnikova, R. A. Ferre, W. Liu, B. Bolanos, K. F. Fennell, J. Nicki, T. Craig, Y. Zhu, A. E. Stewart, C. M. Steppan

This study evaluates nirmatrelvir's in vitro efficacy against SARS-CoV-2 variants, finding it maintains potency against Omicron and other variants.

bioRxiv · Jan 17, 2022Biochemistry

Discovery of a Novel Inhibitor of Coronavirus 3CL Protease as a Clinical Candidate for the Potential Treatment of COVID-19

B. Boras, R. M. Jones, B. J. Anson, D. Arenson, L. Aschenbrenner, M. A. Bakowski, N. Beutler, J. Binder, E. Chen, H. Eng, J. Hammond, R. Hoffman, E. P. Kadar, R. Kania, E. Kimoto, , M. E. McGrath

This study identifies PF-00835321 as a potent inhibitor of SARS-CoV-2 3CL protease with in vitro antiviral activity and clinical evaluation potential.

bioRxiv · Sep 12, 2020 · PreprintPharmacology & Toxicology

Acoustic Ejection Mass Spectrometry for High-Throughput Analysis

H. Zhang, C. Liu, W. Hua, L. P. Ghislain, J. Liu, L. Aschenbrenner, S. Noell, K. Dirico, L. F. Lanyon, C. M. Steppan, D. W. Arnold, T. R. Covey, S. S. Datwani, M. D. Troutman

The paper introduces a mass spectrometry platform combining acoustic droplet ejection, open-port interface, and electrospray ionization for high-speed, label-free analysis across multiple applications.

bioRxiv · Jan 28, 2020Biochemistry