Author

J. Hammond

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Immunology· 2 Evolutionary Biology· 1 Pharmacology & Toxicology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:host-pathogen & immune response· 4 Organism:plant (other)· 4 Research Focus:ecology & biodiversity· 2 Research Focus:gene regulatory network inference· 2 Assay:metagenomics· 2 Organism:mouse· 2 Approach:statistical model· 2

Frequent Co-Authors

A. Bottrill· 2 shared A. Murphy· 2 shared A. Zagrajek· 2 shared C. Conceicao· 2 shared D. Bailey· 2 shared D. Bialy· 2 shared D. Scanlan· 2 shared E. Tchilian· 2 shared

Activity by Year

2019-2024 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersMicrobiology

A. Bottrill

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Prolonged heat stress in Brassica napus during flowering negatively impacts yield and alters glucosinolate and sugars metabolism

M. Kourani, M. Anastasiadi, J. Hammond, F. Mohareb

This study examines how prolonged heat stress during flowering in Brassica napus affects yield and metabolic pathways, revealing changes in glucosinolate and sugar metabolism.

bioRxiv · Apr 1, 2024Plant Biology

Evolutionary genomics reveals variation in structure and genetic content implicated in virulence and lifestyle in the genus Gaeumannomyces

R. Hill, M. Grey, M. Olivera Fedi, D. P. Smith, S. J. Ward, G. Canning, N. Irish, J. Smith, V. McMillan, J. Hammond, S.-J. Osborne, T. Chancellor, D. Swarbreck, N. Hall, J. Palma-Guerrero, , M. McMullan

This study generates high-quality genome assemblies for Gaeumannomyces species, revealing virulence lineage variation and genomic features linked to pathogenicity and lifestyle.

bioRxiv · Feb 15, 2024Evolutionary Biology

Meta-exoproteomics identifies active plant-microbe interactions operating in the rhizosphere

I. D. E. A. Lidbury, S. Raguideau, S. Lui, A. Murphy, R. Stark, C. Borsetto, T. Fraser, A. Goodall, A. Bottrill, A. M. E. Jones, G. Bending, M. Tibbett, J. Hammond, C. Quince, D. Scanlan, , E. Wellington

This study uses meta-exoproteomics to identify active plant-microbe interactions in the rhizosphere of Brassica spp., revealing metabolic shifts linked to plant growth.

bioRxiv · Sep 1, 2021 · PreprintMicrobiology

Discovery of a Novel Inhibitor of Coronavirus 3CL Protease as a Clinical Candidate for the Potential Treatment of COVID-19

B. Boras, R. M. Jones, B. J. Anson, D. Arenson, L. Aschenbrenner, M. A. Bakowski, N. Beutler, J. Binder, E. Chen, H. Eng, J. Hammond, R. Hoffman, E. P. Kadar, R. Kania, E. Kimoto, , M. E. McGrath

This study identifies PF-00835321 as a potent inhibitor of SARS-CoV-2 3CL protease with in vitro antiviral activity and clinical evaluation potential.

bioRxiv · Sep 12, 2020 · PreprintPharmacology & Toxicology

A COVID-19 vaccine candidate using SpyCatcher multimerization of the SARS-CoV-2 spike protein receptor-binding domain induces potent neutralising antibody responses

T. K. Tan, P. Rijal, R. Rahikainen, A. Keeble, L. Schimanski, S. Hussain, R. Harvey, J. Hayes, J. Edwards, R. McLean, V. Martini, M. Pedrera, N. Thakur, C. Conceicao, I. Dietrich, , R. Owens

This study develops a vaccine candidate using SpyCatcher technology to display the SARS-CoV-2 RBD, showing strong neutralizing antibody responses in mice and pigs.

bioRxiv · Aug 31, 2020Immunology

Protective porcine influenza virus-specific monoclonal antibodies recognize similar haemagglutinin epitopes as humans

B. Holzer, P. Rijal, A. McNee, B. Paudyal, B. Clark, T. Manjegowda, F. J. Salguero, E. Bessell, J. C. Schwartz, K. Moffat, M. Pedrera, S. P. Graham, M. B.-D. Placido, R. M. La Ragione, W. Mwangi, , E. Tchilian

This study generates pig-specific monoclonal antibodies against H1N1pdm09 influenza virus that target human-like HA epitopes and reduce disease severity in pigs.

bioRxiv · Jul 21, 2020Immunology

The SARS-CoV-2 Spike protein has a broad tropism for mammalian ACE2 proteins

C. Conceicao, N. Thakur, S. Human, J. T. Kelly, L. Logan, D. Bialy, S. Bhat, P. Stevenson-Leggett, A. Zagrajek, P. Hollinghurst, M. Varga, C. Tsirigoti, J. Hammond, H. J. Maier, E. Bickerton, , D. Bailey

This study shows SARS-CoV-2 Spike protein can bind to ACE2 receptors from multiple mammals, indicating broad host tropism and potential for zoonotic transmission.

bioRxiv · Jun 17, 2020Microbiology

Novel mechanisms for phosphate acquisition in abundant rhizosphere-dwelling Bacteroidetes

I. D. E. A. Lidbury, D. Scanlan, A. Murphy, A. Bottrill, A. Jones, M. Tibbett, G. Bending, J. Hammond, E. Wellington

This study identifies novel phosphate mobilization mechanisms in Flavobacterium strains from the rhizosphere, including unique phosphatases, hypothetical genes, and SusCD transporters.

bioRxiv · Jul 31, 2019 · PreprintMicrobiology