Author

S. Okano

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. R. White· 1 shared A. SheelaNair· 1 shared B. D. Wines· 1 shared B. Greenhouse· 1 shared C. Cuni-Lopez· 1 shared C. Ferguson· 1 shared D. Andrew· 1 shared E. Arinaitwe· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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1 shared paperCell Biology

A. R. White

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Author profile →

3 papers

Recent·Most cited

A novel patient-derived cellular platform for validating microglia-targeted therapeutics for Alzheimer's disease

C. Cuni-Lopez, R. Stewart, S. Okano, G. L. Redlich, M. W. Appleby, A. R. White, H. Quek

This study develops a patient-derived cellular platform to test microglia-targeted therapeutics for Alzheimer's disease, finding that 3D models better distinguish drug responses between healthy and patient donors.

bioRxiv · Aug 17, 2023 · PreprintCell Biology

Age dependent changes in circulating Tfh cells influence the development of functional antibodies to malaria in children.

J.-A. Chan, J. Loughland, L. de la Parte, S. Okano, I. Ssewanyana, M. Nalubega, F. Nankya, K. Musinguzi, J. Rek, E. Arinaitwe, P. Tipping, P. Bourke, D. Andrew, N. Dooley, A. SheelaNair, , M. J. Boyle

The paper examines age-related changes in Tfh cells and their impact on antibody development against malaria in children, finding age-dependent shifts in Tfh cell subsets and antibody responses.

bioRxiv · Dec 12, 2021Immunology

An inverted Caveolin-1 topology defines a novel exosome secreted from prostate cancer cells

N. Ariotti, Y. Wu, S. Okano, Y. Gambin, J. Follett, J. Rae, C. Ferguson, R. D. Teasdale, K. Alexandrov, F. A. Meunier, M. M. Hill, R. G. Parton

The paper identifies an inverted Cav1 topology in exosomes secreted by prostate cancer cells, revealing a non-canonical autophagy pathway involved in disease progression.

bioRxiv · Mar 19, 2020Cell Biology