Author

J. Rek

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Research Focus:cell type annotation· 3 Assay:proteomics· 3 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

B. Greenhouse· 4 shared G. Dorsey· 3 shared I. Ssewanyana· 3 shared M. Kamya· 3 shared C. Drakeley· 2 shared E. Arinaitwe· 2 shared F. Nankya· 2 shared J. Beeson· 2 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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4 shared papersImmunology

B. Greenhouse

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4 papers

Recent·Most cited

Disease Tolerance Acquired Through Repeated Plasmodium Infection Involves Epigenetic Reprogramming of Innate Immune Cells

J. Nideffer, M. Ty, M. Donato, J. Rek, R. Kajubi, X. Ji, H. Maecker, F. Nankya, K. Musinguzi, K. Press, B. Greenhouse, M. Kamya, M. E. Feeney, G. Dorsey, P. Utz, , P. Jagannathan

The paper shows that repeated Plasmodium infection leads to epigenetic changes in innate immune cells, which suppress inflammation and confer long-term disease tolerance in Ugandan children.

bioRxiv · Apr 19, 2023 · PreprintImmunology

Proteome-wide antigenic profiling in Ugandan cohorts identifies associations between age, exposure intensity, and responses to repeat-containing antigens in Plasmodium falciparum

M. Raghavan, K. L. Kalantar, E. Duarte, N. Teyssier, S. Takahashi, A. F. Kung, J. V. Rajan, J. Rek, K. K. A. Tetteh, C. Drakeley, I. Ssewanyana, I. Rodriguez-Barraquer, B. Greenhouse, J. L. DeRisi

The paper profiles antibody responses to Plasmodium falciparum antigens in Ugandan cohorts, finding that repeat-containing antigens show stronger exposure-dependent responses and shared cross-reactive motifs.

bioRxiv · Jun 24, 2022Immunology

Age dependent changes in circulating Tfh cells influence the development of functional antibodies to malaria in children.

J.-A. Chan, J. Loughland, L. de la Parte, S. Okano, I. Ssewanyana, M. Nalubega, F. Nankya, K. Musinguzi, J. Rek, E. Arinaitwe, P. Tipping, P. Bourke, D. Andrew, N. Dooley, A. SheelaNair, , M. J. Boyle

The paper examines age-related changes in Tfh cells and their impact on antibody development against malaria in children, finding age-dependent shifts in Tfh cell subsets and antibody responses.

bioRxiv · Dec 12, 2021Immunology

Impact of a rapid decline in malaria transmission on antimalarial IgG subclasses and avidity

I. Ssewanyana, J. Rek, I. Rodriguez, L. Wu, E. Arinaitwe, J. Nankabirwa, J. Beeson, H. Mayanja- Kizza, P. Rosenthal, G. Dorsey, M. Kamya, C. Drakeley, B. Greenhouse, K. K. Tetteh

The paper examines how malaria transmission decline affects antimalarial IgG subclasses and avidity in Ugandans, finding age-related changes in IgG decay, subclass ratios, and avidity dynamics.

bioRxiv · Jun 26, 2020Immunology