Exposure of Greenlandic Inuit and South African VhaVenda men to the persistent DDT metabolite is associated with an altered sperm epigenome at regions implicated in paternal epigenetic transmission and developmental disease - a cross-sectional study
Ariane Lismer, Xiaojian Shao, Marie-Charlotte Dumargne, Christine Lafleur, Romain Lambrot, Donovan Chan, Gunnar Vase Toft, Jens Peter Bonde, Amanda J MacFarlane, Riana Bornman, Natalie Hildegard Aneck-Hahn, S. Patrick, Janice L. Bailey, Christiaan de Jager, Vanessa Dumeaux, , Sarah Kimmins
This study examines the association between p,p-DDE exposure and sperm epigenome alterations in Greenlandic Inuit and South African VhaVenda men, identifying potential impacts on future generations.
bioRxiv · Aug 15, 2022 · PreprintGenomics