Membrane Lipids Augment Cell Envelope Stress Signaling and Resistance to Antibiotics and Antimicrobial Peptides in Enterococcus faecalis
W. R. Miller, A. Nguyen, K. V. Singh, S. Rizvi, A. Khan, S. G. Erickson, S. L. Egge, M. Cruz, A. Q. Dinh, L. Diaz, R. Zhang, L. Xu, D. A. Garsin, Y. Shamoo, C. A. Arias
This study identifies the MadRS system and its operon madEFG as mediators of resistance to antimicrobial peptides and antibiotics in Enterococcus faecalis, linking membrane lipid changes to stress response and virulence.
bioRxiv · Oct 17, 2023 · PreprintMicrobiology