Deep transcriptome annotation suggests that small and large proteins encoded in the same genes often cooperate
S. Samandi, A. V. Roy, V. Delcourt, J.-F. Lucier, J. Gagnon, M. C. Beaudoin, B. Vanderperre, M.-A. Breton, J.-F. Jacques, M. Brunelle, J. Motard, I. Gagnon-Arsenault, I. Fournier, A. Ouangraoua, D. J. Hunting, , X. Roucou
The paper identifies alternative open reading frames (altORFs) that encode small proteins, showing functional cooperation with larger proteins from the same gene.
bioRxiv · Sep 22, 2017Biochemistry