I. Fournier

The Colibactin-Producing Escherichia coli alters the tumor microenvironment to immunosuppressive lipid overload facilitating colorectal cancer progression and chemoresistance.

This study shows that Colibactin-producing Escherichia coli creates an immunosuppressive lipid-rich tumor microenvironment that promotes colorectal cancer progression and chemoresistance.

Establishment and characterization of a tumoroid biobank derived from dog patients' mammary tumors for translational research

This paper establishes a canine mammary tumoroid biobank that mirrors human breast cancer in molecular and histological features, demonstrating its utility as a preclinical drug screening model.

Towards high spatially resolved microproteomics using expansion microscopy

This paper develops a method to combine expansion microscopy with microproteomics to enable spatially resolved protein analysis at high resolution.

Robot-Assisted SpiderMass for in vivo Real-Time Topography Mass Spectrometry Imaging

This paper introduces a robotic system for in vivo real-time topography mass spectrometry imaging, demonstrating 3D whole-body mouse imaging without image fusion.

Overall patient's survival of glioblastoma associated to molecular markers: a pan-proteomic prospective study

This paper identifies three molecular groups of glioblastoma (GBM) associated with different survival outcomes using pan-proteomic analysis and validates prognostic markers for improved patient stratification.

Preneoplastic lesions fimbria pan-proteomic studies establish the fimbriectomy benefit for BRCA1/2 patients and identify early diagnosis markers of HGSC

The paper analyzes proteomic data from preneoplastic lesions in fallopian tubes to identify early diagnostic markers for HGSC and support fimbriectomy benefits for BRCA1/2 patients.

On-tissue spatially-resolved glycoproteomics guided by N-glycan imaging reveal global dysregulation of canine glioma glycoproteomic landscape

This paper develops a spatially-resolved glycoproteomics approach combining MALDI imaging and LC-MS/MS to identify glycan patterns in canine gliomas, revealing dysregulated glycosylation in tumor and necrotic regions.

Deep transcriptome annotation suggests that small and large proteins encoded in the same genes often cooperate

The paper identifies alternative open reading frames (altORFs) that encode small proteins, showing functional cooperation with larger proteins from the same gene.