Author

X. Roucou

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Assay:proteomics· 4 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:differential expression· 1

Frequent Co-Authors

A. Meller· 3 shared D. Levesque· 2 shared F.-M. Boisvert· 2 shared M. S. Scott· 2 shared A. A. Cohen· 1 shared A. Castonguay· 1 shared A. Ouangraoua· 1 shared A. V. Roy· 1 shared

Activity by Year

2017-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersCell Biology

A. Meller

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

The Pseudogene RPS27AP5 Reveals Novel Ubiquitin and Ribosomal Protein Variants Involved in Specialised Ribosomal Functions.

A. Meller, D. Levesque, J. Raisch, E. Fafard-Couture, M. S. Scott, X. Roucou, F.-M. Boisvert

The paper identifies a functional pseudogene, RPS27AP5, that produces ubiquitin and ribosomal protein variants involved in specialized ribosomal functions and transcriptional regulation.

bioRxiv · Feb 5, 2024 · PreprintCell Biology

CRISPR/Cas9-mediated knockout of the ubiquitin variant UbKEKS reveals a role in regulating nucleolar structures and composition.

J. Frion, A. Meller, G. Marbach, D. Levesque, X. Roucou, F.-M. Boisvert

This study shows that UbKEKS regulates nucleolar structure and composition by affecting lamin A accumulation, apoptotic regulator sequestration, and nucleolar morphology.

bioRxiv · Mar 17, 2023 · PreprintCell Biology

Decoupling of mRNA and protein expression in aging brains reveals the age-dependent adaptation of specific gene subsets

I. Khatir, M. A. Brunet, A. Meller, F. Amiot, T. Patel, X. Lapointe, J. A. Lopez, N. Guilloy, A. Castonguay, M. A. Husain, J. St Germain, F. M. Boisvert, M. Plourde, X. Roucou, B. Laurent

The paper examines mRNA and protein expression changes in aging mouse brains, finding age-dependent gene subset adaptations with distinct transcriptional and translational responses.

bioRxiv · Oct 2, 2022Biochemistry

Deep transcriptome annotation suggests that small and large proteins encoded in the same genes often cooperate

S. Samandi, A. V. Roy, V. Delcourt, J.-F. Lucier, J. Gagnon, M. C. Beaudoin, B. Vanderperre, M.-A. Breton, J.-F. Jacques, M. Brunelle, J. Motard, I. Gagnon-Arsenault, I. Fournier, A. Ouangraoua, D. J. Hunting, , X. Roucou

The paper identifies alternative open reading frames (altORFs) that encode small proteins, showing functional cooperation with larger proteins from the same gene.

bioRxiv · Sep 22, 2017Biochemistry