MicrobiologybioRxiv
Powassan Viruses Spread Cell to Cell During Direct Isolation from IxodesTicks and Persistently Infect Human Brain Endothelial Cells and Pericytes
J. N. Conde, S. Sanchez-Vicente, N. Saladino…·E. R. Mackow
This study isolates and characterizes POWVs from ticks, showing they spread cell-to-cell in culture and infect human brain endothelial cells and pericytes, leading to persistent infection and inflammatory responses.
DOI 10.1128/jvi.01682-21