Cancer-associated fibroblast-derived ROR2 induces WNT/PCP activation and polarized migration in receiving gastric cancer cells.
S. Rogers, C. Zhang, V. Anagnostidis, F. Gielen, M. Fishel, S. Scholpp
The paper shows that cancer-associated fibroblasts transfer ROR2 to gastric cancer cells, activating WNT/PCP signaling and promoting migration.
bioRxiv · Apr 7, 2022 · PreprintCancer Biology