Author

S. Spitz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Assay:organoid / primary culture· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

P. Ertl· 4 shared C. Jordan· 3 shared M. Harasek· 3 shared H. D. Wanzenboeck· 2 shared H. Redl· 2 shared J. C. Schwamborn· 2 shared P. Schuller· 2 shared S. Bolognin· 2 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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4 shared papersBioengineering

P. Ertl

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Author profile →

4 papers

Recent·Most cited

Development of a multi-sensor integrated midbrain organoid-on-a-chip platform for studying Parkinson's disease

S. Spitz, S. Bolognin, K. Brandauer, J. Fuessl, P. Schuller, S. Schobesberger, C. Jordan, B. Schaedl, J. Grillari, H. D. Wanzenboeck, T. Mayr, M. Harasek, J. C. Schwamborn, P. Ertl

This study develops a multi-sensor organ-on-a-chip platform to monitor Parkinson's disease-related phenotypes in midbrain organoids and demonstrates its utility in drug screening.

bioRxiv · Aug 19, 2022 · PreprintBioengineering

Microvasculature-on-a-Chip: Bridging the interstitial blood-lymph interface via mechanobiological stimuli

B. Bachmann, S. Spitz, C. Jordan, P. Schuller, H. D. Wanzenboeck, B. Haddadi Sisakht, M. Harasek, H. Redl, W. Holnthoner, P. Ertl

This paper introduces a microvascular-on-a-chip model that mimics the interstitial blood-lymph interface, showing increased vessel sprouting under dynamic mechanobiological stimulation.

bioRxiv · Apr 8, 2021 · PreprintBioengineering

Establishment of a human three-dimensional chip-based chondro-synovial co-culture joint model for reciprocal cross-talk studies in arthritis research

M. Rothbauer, R. A. Byrne, S. Schobesberger, I. Olmos Calvo, A. Fischer, E. Reihs, S. Spitz, B. E. M. Bachmann, F. Sevelda, J. Holinka, W. Holnthoner, H. Redl, S. Toegel, R. Windhager, H. P. Kiener, P. Ertl

This study establishes a 3D microfluidic co-culture model of synovial and chondral organoids to study reciprocal cross-talk in arthritis, showing enhanced cartilage physiology and cytokine responses in co-cultures.

bioRxiv · Feb 19, 2021Bioengineering

Cultivation and characterization of human midbrain organoids in sensor integrated microfluidic chips

S. Spitz, C. Zanetti, S. Bolognin, M. N. Muwanigwa, L. M. Smits, E. Berger, C. Jordan, M. Harasek, J. C. Schwamborn, P. Ertl

This study develops a sensor-integrated microfluidic platform for long-term cultivation and non-invasive monitoring of human midbrain organoids, showing sustained viability and dopaminergic differentiation over 50 days.

bioRxiv · Dec 10, 2019 · PreprintBioengineering