Cell BiologybioRxiv
mTORC1 induces eukaryotic translation initiation factor 4E interaction with TOS-S6 kinase 1 and its activation
S. T. Majeed, A. Batool, R. Majeed…·K. I. Andrabi
The paper shows that phosphorylated eIF4E interacts with the TOS motif of S6K1, relieving its auto-inhibition and enabling activation independent of mTORC1.
DOI 10.1080/15384101.2021.1901038