Author

S. Tholen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Assay:imaging· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Rabiee· 2 shared M. L. Zhao· 2 shared M. N. Teruel· 2 shared Z. Bahrami-Nejad· 2 shared A. Kraus· 1 shared A. Miucci· 1 shared D. Hunerdosse· 1 shared E. Bielczyk-Maczynska· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCell Biology

A. Rabiee

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Author profile →

4 papers

Recent·Most cited

Interactors and effects of overexpressing YlxR/RpnM, a conserved RNA binding protein in cyanobacteria

L. Hemm, A. Miucci, M. Riediger, S. Tholen, A. Kraus, J. Georg, O. Schilling, W. R. Hess

This study identifies RNA-binding partners and functions of YlxR/RpnM in cyanobacteria, showing its role in RNA maturation, cell division, and nitrogen metabolism.

bioRxiv · Jan 6, 2024 · PreprintMicrobiology

Early enforcement of cell identity by a functional component of the terminally differentiated state

Z. Bahrami-Nejad, T. Chen, S. Tholen, Z.-b. Zhang, A. Rabiee, M. L. Zhao, M. Teruel

The paper shows that FABP4, a core component of mature adipocytes, drives differentiation by forming positive feedback loops with PPARG, enabling irreversible commitment to the adipocyte state.

bioRxiv · Jan 3, 2020 · PreprintCell Biology

Flattening of diurnal glucocorticoid oscillations causes Cd36 and insulin-mediated obesity

S. Tholen, K. M. Kovary, A. Rabiee, E. Bielczyk-Maczynska, W. Yang, F. B. Kraemer, M. N. Teruel

This study shows that flattened diurnal glucocorticoid oscillations lead to obesity and diabetes by dysregulating lipid metabolism via Cd36 and insulin signaling in adipose tissues.

bioRxiv · Jan 2, 2020Physiology

Transcription factor dynamics reveals a circadian code for fat cell differentiation

Z. Bahrami-Nejad, M. L. Zhao, S. Tholen, D. Hunerdosse, K. E. Tkach, S. van Schie, M. Chung, M. N. Teruel

The paper shows that pulsatile circadian hormone signals inhibit adipocyte differentiation, while persistent signals promote it, revealing a circadian code for fat cell differentiation.

bioRxiv · Jan 11, 2018Physiology