BioengineeringbioRxivPreprint
De novo design of high-affinity protein binders to bioactive helical peptides
S. Vazquez Torres, P. J. Y. Leung, I. D. Lutz…·D. Baker
This paper designs high-affinity protein binders for bioactive helical peptides using deep learning and generative models, achieving picomolar affinity without experimental optimization.
DOI 10.1101/2022.12.10.519862