Author

S. Zimmer

Primary ORCID profile (0000-0002-3784-2063 · 3 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

S. ZimmeriD3 papers · University Medical Center of the Johannes Gutenberg University Mainz

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:mouse· 1 Organism:non-human primate· 1

Frequent Co-Authors

A. Pfeifer· 2 shared D. Nehl· 2 shared F. Bakhtiary· 2 shared F. Jansen· 2 shared G. Nickenig· 2 shared M. R. Hosen· 2 shared P. R. Goody· 2 shared D. Christmann· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersCell Biology

A. Pfeifer

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Author profile →

2 papers

Recent·Most cited

Porcine and human aortic valve endothelial and interstitial cell isolation and characterization

D. Nehl, P. R. Goody, K. Maus, A. Pfeifer, E. Aikawa, F. Bakhtiary, S. Zimmer, G. Nickenig, F. Jansen, M. R. Hosen

This study isolates and characterizes human and porcine aortic valve endothelial and interstitial cells, comparing their gene expression and calcification responses.

bioRxiv · Dec 1, 2022 · PreprintCell Biology

Aortic valve disease augments vesicular microRNA-145-5p to regulate the calcification of valvular interstitial cells via cellular crosstalk

P. R. Goody, D. Christmann, D. Goody, D. Nehl, K. Backer, K. Wilhelm-Juengling, S. Uchida, J. B. Moore, S. Zimmer, F. Bakhtiary, A. Pfeifer, E. Latz, G. Nickenig, F. Jansen, M. R. Hosen

This study identifies miR-145-5p as a key regulator of aortic valve calcification through EV-mediated crosstalk, showing it suppresses ZEB2 to enhance ALPL expression and promote calcification in valvular interstitial cells.

bioRxiv · Nov 29, 2022 · PreprintCell Biology