Author

y. SIMONI

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 2 Organism:human· 2 Assay:scRNA-seq· 2 Assay:bulk RNA-seq· 1 Assay:CITE-seq· 1 Research Focus:clustering· 1 Approach:deep learning· 1

Frequent Co-Authors

E. W. NEWELL· 3 shared D. S. W. TAN· 2 shared S. LI· 2 shared A. HEIT· 1 shared A. J. Tyznik· 1 shared A. TAKANO· 1 shared C. Y. LOH· 1 shared E. Becht· 1 shared

Activity by Year

2019-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersImmunology

E. W. NEWELL

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Author profile →

3 papers

Recent·Most cited

Bystander CD4+ T cells infiltrate human tumors and are phenotypically distinct

y. SIMONI, S. LI, S. ZHUANG, A. HEIT, S.-L. KOO, I.-T. CHOW, W. W. KWOK, I. B. TAN, D. S. W. TAN, E. W. NEWELL

The paper identifies bystander CD4+ T cells in human tumors, showing they are phenotypically distinct and express CD39, correlating with CD8+ TILs specific for non-cancer antigens.

bioRxiv · Jul 15, 2020 · PreprintImmunology

A targeted multi-omic analysis approach measures protein expression and low abundance transcripts on the single cell level

F. Mair, J. R. Erickson, V. Voillet, Y. Simoni, T. Bi, A. J. Tyznik, J. Martin, R. Gottardo, E. W. Newell, M. Prlic

The paper introduces a targeted multi-omic approach that measures protein and low abundance transcript expression on single cells, requiring less sequencing depth than whole transcriptome methods.

bioRxiv · Jul 14, 2019Immunology

Partial absence of PD-1 expression by tumor-specific CD8+ T cells in EBV-driven lymphoepithelioma-like carcinoma: a case report

Y. SIMONI, E. Becht, S. Li, C. Y. LOH, J. P. S. YEONG, T. K. H. LIM, A. TAKANO, D. S. W. TAN, E. W. NEWELL

This study reports the absence of PD-1 expression on EBV-specific CD8+ T cells in LELC, suggesting anti-PD1/PD-L1 therapy may not be effective for this cancer type.

bioRxiv · Jul 9, 2019 · PreprintCancer Biology