Author

Sahar Abdelkarim

Rosalind Franklin Institute

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Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1

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Courtney J. Mycroft‐WestiD· 1 shared Helen M. E. DuyvesteyniD· 1 shared Liang WuiD· 1 shared Mark Andrew SkidmoreiD· 1 shared Neha S. GandhiiD· 1 shared Raymond J. OwensiD· 1 shared

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2024-2024 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperBiochemistry

Courtney J. Mycroft‐WestORCID

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1 paper

Recent·Most cited

BiochemistryNature CommunicationsPeer-reviewedFeb 13, 2024

Structural and mechanistic characterization of bifunctional heparan sulfate N-deacetylase-N-sulfotransferase 1

Courtney J. Mycroft‐West, Sahar Abdelkarim, Helen M. E. Duyvesteyn…·Liang Wu

This study determines the structure of NDST1, revealing its catalytic domains and a non-catalytic N-terminal domain, and proposes a mechanism for its function.

29 citationstop 4%

humanstructural biology

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