BiochemistryWellcome Open ResearchPeer-reviewed
Quantitative cross-linking/mass spectrometry reveals subtle protein conformational changes
Zhuo Angel Chen, Lutz Fischer, Salman Tahir…·Juri Rappsilber
This study develops QCLMS to detect protein conformational changes by analyzing cross-linking yields and introduces methods to distinguish minor and major changes.
DOI 10.12688/wellcomeopenres.9896.1