GeneticsPLoS Computational BiologyPeer-reviewed
The ability of transcription factors to differentially regulate gene expression is a crucial component of the mechanism underlying inversion, a frequently observed genetic interaction pattern
Saman Amini, Annika Jacobsen, Olga Ivanova…·Patrick Kemmeren
The paper compares genetic interaction patterns between gene-specific transcription factors and signaling genes in yeast, finding inversion is more common in transcription factors due to differential regulation.
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