Author

Sandra Francis

Srinivas University

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Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:E. coli· 1 Assay:metabolomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Anoop Kumar G. VelikkakathiD· 1 shared Michihiro ArakiiD· 1 shared Niyas RehmaniD· 1 shared Rahad Rehas· 1 shared Shuhei NodaiD· 1 shared Yuttamol Muangkram· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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1 shared paperSystems Biology

Anoop Kumar G. VelikkakathORCID

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Recent·Most cited

Systems BiologybioRxivPreprintSep 18, 2026

Threonine Supplementation Reduces Methylglyoxal Overflow by Increasing Glycolysis Flux at the Payoff Phase: A Metabolic Modeling Analysis

Sandra Francis, Rahad Rehas, Yuttamol Muangkram…·Michihiro Araki

This study uses metabolic modeling to show that threonine supplementation reduces methylglyoxal overflow in E. coli by enhancing glycolytic flux, with limited effect under hypoxic conditions.

DOI 10.64898/2026.09.17.751990

E. colimetabolomics

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