Cancer BiologybioRxivPreprint
Italia: A PARP-Directed Auger Electron-Emitting Agent for Targeted Radionuclide Therapy of Cancer
Sreelakshmi Unnikrishnan, Chiara Rua, G.C. Li…·Bart T. Cornelissen
This paper describes the design, synthesis, and evaluation of [123I]Italia, a PARP-targeted radionuclide therapy agent showing potent PARP1 inhibition and cancer cell uptake.