Author

Sarah K Denny

Scribe Therapeutics;

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:ATAC-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Addison V Wright· 1 shared Alicia Schep· 1 shared Allison Didychuk· 1 shared Ashley E Graham· 1 shared Ben Demaree· 1 shared Benjamin L Oakes· 1 shared Cécile Fortuny· 1 shared Christie C Sze· 1 shared

Activity by Year

2015-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperMolecular Biology

Addison V Wright

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintNov 12, 2026

Comprehensive engineering of the CasX-Editor to generate a therapeutically optimized genome editor

Addison V Wright, Sean A Higgins, Elizabeth J Bailey…·Benjamin L Oakes

This paper engineers the CasX-Editor to create a more potent and specific genome editor for therapeutic use, showing improved activity and reduced off-target effects in nonhuman primates.

DOI 10.64898/2026.11.10.765514

non-human primateexperimental assay

𝕏 PostBluesky

GenomicsGenome ResearchPeer-reviewedNov 1, 2015

Structured nucleosome fingerprints enable high-resolution mapping of chromatin architecture within regulatory regions

Alicia Schep, Jason D Buenrostro, Sarah K Denny…·William J Greenleaf

The paper introduces NucleoATAC, an algorithm using ATAC-seq data to precisely map nucleosome positions and occupancy in yeast and human cells.

DOI 10.1101/gr.192294.115

yeasthuman

𝕏 PostBluesky