NeurosciencebioRxivPreprint
Systems-level investigation of mucopolysaccharidosis IIIA identifies deficient synaptic activity as a key driver of disease progression
Alon M. Douek, Adrian Salavaty, Florian Kreuder…·Jan Kaslin
The paper uses a zebrafish model of MPS IIIA to identify synaptic activity deficiencies as a key driver of disease progression through systems-level omics analyses and a novel bioinformatic tool.
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