Systems BiologyProceedings of the National Academy of SciencesPeer-reviewed
Bacteriophage self-counting in the presence of viral replication
Tianyou Yao, Seth Coleman, Thu Vu Phuc Nguyen…·Oleg A. Igoshin
The paper shows that bacteriophage lambda uses viral replication to reliably count infecting genomes, leading to lysogenic or lytic decisions based on multiplicity of infection.
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