BiochemistrybioRxivPreprint
HP1 dimerization drives the condensation and segregation of H3K9me-marked chromatin
Karthik Eswara, Jennifer I. Semple, Francesca Rivas-Cuestas…·Wolfgang Fischle
This study shows that HP1 dimerization drives H3K9me chromatin condensation and segregation, while LLPS stabilizes foci, and reveals a decoupling between heterochromatin and transcriptional regulation.
DOI 10.1101/2025.11.13.687974