NeurosciencebioRxivPreprint
TAF1-gene editing impairs Purkinje cell morphology and function
Udaiyappan Janakiraman, Jie Yu, Aubin Moutal…·Mark A. Nelson
This paper develops a novel rat model for TAF1 ID syndrome using CRISPR-Cas9 and lentiviral transduction, showing Purkinje cell hypoplasia and behavioral deficits.
1 citation