Author

Shiyu Xia

Department of Chemical and Biomolecular Engineering, College of Chemistry, University of California Berkeley; Berkeley, CA, 94720, USA

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

Albert Qiang· 1 shared Ali Ahmed Diaz· 1 shared Andrew C. LuiD· 1 shared Bo GuiD· 1 shared Daniel J. SiegwartiD· 1 shared Evan Zhang· 1 shared Haley Larson· 1 shared Hao ZhuiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperSynthetic Biology

Albert Qiang

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2 papers

Recent·Most cited

Multispecies transport shapes electrochemical environments in perforated cells

Yikang Guan, Hengyu Li, Miao Shi, Kenneth Sajbel, Yi Bryon Gao, Shiyu Xia

The paper models multispecies transport through gasdermin pores to explain how pore formation leads to cell swelling and osmotic changes.

bioRxiv · Nov 4, 2026 · PreprintBiophysics

Engineered protein circuits for cancer therapy

Andrew C. Lu, Lukas Moeller, Stephen Moore, Kevin Ho, Victoria Tobin, Albert Qiang, Evan Zhang, Zhijie Li, Mengmeng Wang, Shiyu Xia, Mark W. Budde, Haley Larson, Ali Ahmed Diaz, Bo Gu, James M. Linton, , Michael B. Elowitz

This paper engineers protease-based protein circuits that selectively kill RAS-mutant cancer cells and suppress tumors, showing resistance reduction and cytotoxicity independent of oncogene addiction.

bioRxiv · Apr 16, 2025 · PreprintSynthetic Biology