BiophysicsbioRxivPreprint
Spatiotemporal Patterns of Active Deformation Reveal Downregulation of Cell-Cell Adhesion in Patient-Derived Colorectal Cancer Organoids with BRAF Mutation
Shogo Nagai, Ryo Suzuki, Go Yamakawa…·Motomu Tanaka
This study shows that BRAF-mutated colorectal cancer organoids have reduced elasticity and increased viscosity, linked to decreased cell-cell adhesion and potential therapeutic implications.
DOI 10.64898/2026.03.07.710277