BiochemistrybioRxivPreprint
Specific interactions with phospho-Ubls and allosteric conformational changes regulate the E3 ligase activity of Parkin
Dipti Ranjan Lenka, Shradha Chaurasiya, Atul Kumar
This study determines the crystal structure of Parkin bound with phospho-NEDD8, revealing how phospho-Ubls and conformational changes regulate Parkin's E3 ligase activity.
DOI 10.1101/2023.11.21.568018