Author

Shuai Jiang

Shandong University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Bioinformatics· 4 Cancer Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 5 Assay:spatial transcriptomics· 3 Research Focus:cell-cell communication· 2 Approach:deep learning· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Bingqiang LiuiD· 2 shared Shuli SuniD· 2 shared Chenghui ZhaoiD· 1 shared Fei Hu· 1 shared Guojun LiiD· 1 shared Guojun Li· 1 shared Hao HongiD· 1 shared Hao HuangiD· 1 shared

Activity by Year

2016-2026 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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2 shared papersBioinformatics

Bingqiang LiuORCID

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Author profile →

6 papers

Recent·Most cited

DiffGSP: reversing mRNA diffusion to unlock high-fidelity spatial transcriptomics

Jixin Liu, Shuli Sun, Yang Xu, Shuai Jiang, Shuhuan Cao, Guojun Li, Xin Zhao, Bingqiang Liu

DiffGSP reverses mRNA diffusion to improve spatial transcriptomics fidelity, revealing fine anatomical structures and spatial gene modules in various tissues.

bioRxiv · Sep 15, 2026 · PreprintBioinformatics

SpaGRD deciphers signaling architectures in spatial transcriptomics using graph reaction-diffusion systems

Jixin Liu, Shuli Sun, Zhitong Chen, Zhengliang Lv, Shuai Jiang, Guojun Li, Bingqiang Liu

SpaGRD models cell-cell communication using graph reaction-diffusion systems, revealing spatially resolved signaling patterns in spatial transcriptomics data.

bioRxiv · Jul 2, 2026 · PreprintBioinformatics

Integrated single-cell and spatial transcriptomic analysis of T cell exhaustion and immunometabolic remodeling in HPV-positive oropharyngeal squamous cell carcinoma

Ke Wang, Nian Hui Deng, Yueqin Tao, Xin Yang, Mujie Yuan, Longhua Gao, Shuai Jiang, Wei Shang, Jing Deng, Lin Wang

This study integrates single-cell and spatial transcriptomics to uncover mechanisms of immune checkpoint resistance in HPV-positive oropharyngeal cancer, identifying a KMT2D-KLF7-PD-L1 axis as a therapeutic target.

bioRxiv · Mar 14, 2026 · PreprintCancer Biology

PlotGDP: an AI Agent for Bioinformatics Plotting

Xiaotong Luo, Ying Shi, Hao Huang, Hongge Wang, Wenyi Cao, Zhixiang Zuo, Qi Zhao, Yueyuan Zheng, Yubin Xie, Shuai Jiang, Jian Ming Ren

PlotGDP provides an AI-powered web server for generating publication-quality bioinformatics plots using natural language commands without requiring coding or environment setup.

bioRxiv · Feb 7, 2026 · PreprintBioinformatics

New insights on human essential genes based on integrated analysis

Hebing Chen, Zhuo Zhang, Shuai Jiang, Ruijiang Li, Wanying Li, Chenghui Zhao, Hao Hong, Xin Huang, Hao Li, Xiaochen Bo

This study integrates multiple analyses to characterize human essential genes and develops a web platform for their comprehensive interpretation.

bioRxiv · Oct 10, 2018 · PreprintGenomics

Reconstruction of ancestral genomes in presence of gene gain and loss.

Pavel Avdeyev, Shuai Jiang, Sergey Aganezov, Fei Hu, Max A. Alekseyev

This paper introduces MGRA2, an improved tool for reconstructing ancestral genomes that handles gene gain/loss and higher breakpoint reuse, outperforming existing methods.

Journal of Computational Biology · Mar 1, 2016Peer-reviewedBioinformatics