Pavel Avdeyev

The T2T-CHM13 reference genome improves read mapping and variant calling across diverse samples, reducing false positives and enabling novel variant discovery.

This study produces chromosome-level genome assemblies for Anopheles coluzzii and Anopheles arabiensis using long-read sequencing and Hi-C scaffolding, improving reference-quality genomes and enabling identification of chromosomal inversion breakpoints.

This study evaluates twelve haplotype callers for NGS viral sequencing, finding they perform poorly under high genetic diversity, with PredictHaplo and PEHaplo showing better accuracy for HIV-like diversity levels.

This paper introduces MGRA2, an improved tool for reconstructing ancestral genomes that handles gene gain/loss and higher breakpoint reuse, outperforming existing methods.